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Second-generation inhibitors demonstrate the involvement of p38 mitogen-activated protein kinase in post-transcriptional modulation of inflammatory mediator production in human and rodent airways

This drug and dosing regimen has demonstrated efficacy in non-human primates after high-dose radiation therapy (Farese 2012) and, as of this writing, Extimia is being evaluated in an open-label randomized phase II clinical study (BCD-017-2), which is expected to conclude in 2013 (ClinicalTrials.gov 2012a)

Multiplex single-cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

doi: 10.1093/nar/gkab1061 Summary Keywords alternative heme biosynthesis, coproporphyrinogen III oxidase, Bacillaceae, Priestia megaterium , anaerobic metabolism Citation Mingers T, Barthels S, Mass V, Acua JMB, Biedendieck R, Cooke A, Dailey TA, Gerdes S, Blankenfeldt W, Dailey HA, Warren MJ, Jahn M and Jahn D (2024) The alternative coproporphyrinogen III oxidase (CgoN) catalyzes the oxygen-independent conversion of coproporphyrinogen III into coproporphyrin III