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Following a single intravenous bolus dose of 0.5 mg/kg in 10 children 4 to 8 years old, the half-life was 5.8 1.6 hours, the average clearance was 0.042 0.01 L/hr/kg, the volume of distribution during the terminal phase (V ) was 0.34 0.12 L/kg and the volume of distribution at steady state (V ss) was 0.26 0.08 L/kg

There was a strong correlation between LiSA and CAP (r = 0.592, p = 30), 37% type 2 diabetes, 53% hyperlipidemia, 59% hypertension, 51% MASH, 48% with PNPLA3 rs738409 CG or GG genotype (linked to higher risk), 58% histologic F1, 22% F2, 13% F3, 7% F4

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