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In TRPV1 expressing sensory neurons and PC12 cells, repeated or high dose capsaicin exposure induces transient mitochondrial damage while simultaneously activating mitophagy and upregulating mitochondrial proteins such as COX IV, Mic60/Mitofilin, and VDAC1, suggesting a coordinated response in which damaged mitochondria are removed and replaced by a healthier organelle pool (38)

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capsule: hydroxypropyl methylcellulose (HPMC, vegan) Recommended daily dose: 1 capsule per day before dinner with a glass of water

Nathalie Chevreau, a biochemist who served as a senior scientific researcher for LifeVantage from 2014 until 2019, told STAT that distributors also routinely made inaccurate claims including, in some cases, that the products could help with cancer at corporate events