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An open-label trial is testing whether a 3-month N-acetylcysteine supplementation in older adults improves glutathione levels, body composition, mitochondrial energetics, dyslipidemia, oxidative stress, protein/glucose metabolism, cognition, and memory (37)

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However, this analysis still could not resolve the exact breakpoints of the deletion, and as such, our attempts to distinguish between identity by descent and recurrence scenarios using breakpoint sequences were not conclusive