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10.3389/fnut.2022.833730

J.BuchananS

554 In the context of the inflammatory microenvironment, HIF-1 has been shown to regulate the expression of inflammatory cytokines

Hence, future directions for developing FBS alternatives should focus on minimizing batch-to-batch variability, optimizing formulations for specific applications, and advancing fully defined and scalable media to enable reliable, ethical, and clinically relevant mammalian cell culture (Subbiahanadar Chelladurai et al., 2021)