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Description

On a normal cysteine-replete diet, 2AB is produced from 2-oxobutyrate (2OB) and glutamate in the presence of aminotransferases 21

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This allows recognition in the context of T cell receptor, both in lupus patients and mice and alters autoreactive T cell phenotype

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Furthermore, it evaluates the current challenges in clinical translation and outlines future directions to advance MB-based biomedical innovations

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[DOI] [PMC free article] [PubMed] [Google Scholar] 347

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