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The high astrocyte specificity of MAO-B around dense-core A plaques enables more precise interrogation of astrocyte-related pathophysiology in the living brain in the context of neurodegenerative disease (Jaisa-Aad et al., 2024)

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Moreover, this effect is most pronounced in the oldest flies (30 days old at time of APAP administration) and is observed in both males and females (Fig

Cells were harvested by centrifugation at 1000 x g for 3 min at room temperature and resuspended in 2 mL fresh HC -Ura-Leu medium containing 50 mM DTT to reduce all roGFP2 sensors before the start of the experiment