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The excitatory amino acid receptors: Their classes, pharmacology, and distinct properties in the function of the central nervous system

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Chronic stress exposure has comprised chronic unpredictable stress models (CUMS), restraint stress for periods ranging from 20 to 56 days, and the acute or chronic administration of anxiety or depressive-inducing exogenous agents such as corticosterone, pentylenetetrazole (-aminobutyrate antagonist), reserpine (monoamine antagonist), 4-aminopyridine (potassium channel blocker), lead, mercuric chloride, and lipopolysaccharide (the major component of the outer membrane of Gram-negative bacteria)