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Pharmacologic inhibition of Hsp90 to prevent GLT-1 degradation as an effective therapy for epilepsy

There is a growing body of evidence suggesting that extracellular pathogens are able to use hosts membrane phospholipids as a source of FAs to assemble their cell membrane, and also degrade phospholipids leading to the production of proinflammatory cytokines ( Helicobacter pylori can glycosylate and use the hosts cholesterol to grow and evade the immune system (Wunder et al., 2006)