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In batch culture process, the recombinant strain W303-1b/FGP also afforded high efficiency in GSH production and reached an intracellular GSH content of 2.27 % after 24-h fermentation

The researchers found that ferredoxin 1 (FDX1) and protein lipoylation are vital regulators of cuproptosis and confirmed that FDX1 is an upstream regulator of the lipoylated protein dihydrolipoamide S-acetyltransferase (DLAT)

Int J Androl 13:1725

Mechanism and gene expression Pickart and colleagues used Broad Institute Connectivity Map data to show GHK-Cu modulates expression of more than 4,000 human genes, with shifts toward patterns associated with younger tissue