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Chip 10 , 19671975 (2010)

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CHAC1-mediated GSH degradation reduces S-glutathionylation of ARF6 at cysteine 90, thereby inactivating ARF6 and enhancing ferroptotic cell death ( Similarly, CHAC1 is upregulated in various kidney disease models ( CHAC1 upregulation was induced by cysteine and methionine deprivation, treatment with erastin and exposure to tunicamycin

Glucosinolates are synthesized from various protein and non-protein amino acids, cysteine and glucose in a manner very similar to the biosynthesis of cyanogenic glucosides except for the addition of sulfur from cysteine