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Clin Cancer Res 19(18):52565257

8 When oxidative stress occurs the ROS scavengers such as GSH, GPx and SOD action was reduced and lipid peroxidation action was increased

Simultaneously, keratinocytes can maintain the homeostasis of the skin system by regulating different PCD pathways, including apoptosis, pyroptosis, necroptosis, and autophagy, to cope with UVR -related damage (Tang et al., 2021)

[4] Human, topical, registered and ongoing: a trial of topical GHK-Cu gel (0.1% w/w) for acute skin wound healing versus vehicle gel in healthy adults was registered on ClinicalTrials.gov in 2026 (NCT07437586)