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Protection against degradation is related to the entrapment of the drug inside core of vesicle which provides protection till reaching site of absorption 27,28

Topical actives (retinoids, benzoyl peroxide, acids)

The gut-liver axis in sepsis: interaction mechanisms and therapeutic potential

Its pathological basis is synovitis, initially manifested as morning stiffness, swelling, and pain in small joints such as hands and feet, which can progress to joint deformities and disability [143]