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Measurement of ROS production Cells were washed in prewarmed PBS and treated with 10 M H 2 DCFDA for 30 min in dark

The therapeutic effects of SAM are associated with the downregulation of the ERK1/2 and STAT3 signaling pathways, both of which are involved in the survival, proliferation, migration, and invasion of cancer cells

Phthalates disrupt ovarian steroidogenesis and have been associated with lower antral follicle counts and reduced IVF success rates. Cigarette smoke: Contains hundreds of toxicants including polycyclic aromatic hydrocarbons that accelerate follicular atresia (egg cell death) and directly damage oocyte DNA

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