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When these fail, energy drops and damaged cells spark inflammation

doi: 10.1371/journal.pone.0086062 30 LiuMLiuSZhangQFangYYuYZhuLet al

Once activated, NF-B translocates from cytoplasm to nucleus where it binds to the DNA promoter sequences of TNF-, IL-1, IL-6, COX-2, and iNOS (Maes 2009