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2 The gut-brain-kidney axis: mechanisms and pathways The gut-brain-kidney axis involves intricate communication between the gastrointestinal tract, central nervous system (CNS), and kidneys through various mechanisms and pathways involving the gut microbiota

En contexto de laboratorio, este compuesto se estudia en proyectos de neurociencia, biologa molecular e investigacin de ritmos biolgicos , siempre en modelos no clnicos y entornos controlados

Taken together, these findings suggest that APR-246 could induce tumor cell death through both reactivation of mutant p53 and inhibition of cellular thiol-dependent redox system proteins (GPX4, TXNDR1, GRX1), providing novel combinatorial strategies for AML therapy