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The continuous struggle to decipher immune responses upon transplantation and infection has been pivotal in the clinical application of organ transplantation ( Subsequently, advancements in immunology played a vital role in developing immunosuppressants, which greatly improved the survival of organ transplants

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Zinc is an essential component of CuZnSOD (SOD1), which accounts for approximately 90% of the total SOD activity and plays a pivotal role in scavenging superoxide radicals and protecting tissues from oxidative damage 86