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doi: 10.1210/en.2004-1064 278 YinHZhuQLiuMTuGLiQYuanJet al

doi:10.1093/ajcp/aqz142

The pioneering work of Langers group in the 1980s led to the development of localized controlled-release therapies for GB, culminating in the FDA approval of the first implantable intra-cavity wafer, Gliadel, in 1996 (142)

Given that AGERAGE signaling is known to activate inflammatory and oxidative pathways 76 , our findings support the interpretation that chronic dietary AGE exposure is associated with testicular redox imbalance