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Iatrogenic iron promotes neurodegeneration and activates self-protection of neural cells against exogenous iron attacks

We tested whether the RNAi-mediated disruption of the DMP in animals would lead to increases in GSSG production and a redox imbalance, and we observed no increase in GSSG disruption of DMP in the JV2 roGFP-sensor strain (Supplementary Fig

Protein synthesis and muscle growth Activation of mTOR pathway: enhances phosphorylation of ribosomal S6 kinase (S6K1) and accelerates protein translation initiation

Other mechanisms are involved in increasing NADPH levels and facilitating the de novo synthesis of glutathione (GSH) and antioxidant enzymes through various mechanisms