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According to our previous study, LAT1 (standing for L-type Amino acid Transporter 1) is indispensable for transport of essential amino acids, general amino acid homeostasis, and consequently, tumor growth ( system, an exchanger that imports cystine, the oxidized form of cysteine, and exports glutamate

doi: 10.1172/jci32741 200 RidkerPMPradhanAMacFadyenJGLibbyPGlynnRJ

Polystyrene petri plates (100 mm x 15 mm) with 20 mL of LB agar and appropriate antibiotics as needed were spread with 300 l of bacterial suspension

Interestingly, the gut metabolic module aspartate degradation I, which converts L-aspartate to oxaloacetate by aspartate aminotransferase, was elevated in SAD patients and the authors hypothesized that bacterial aspartate aminotransferase enzyme activity may represent a link between gut microbiome function and the tryptophan-kynurenine pathway, a key physiological system in psychiatric disorders (Butler et al., 2023)