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doi: 10.3390/brainsci13050739 10 TanHChenJLiYLiYZhongYLiGet al

Oppositely to the anadromous fish which migrate from freshwater to saltwater for growth and development, catadromous fish migrate from saltwater to freshwater

International Journal of Molecular Sciences, 21 (13), 123

In an oncogenic context, the IGF family regulates a number of biological processes such as cancer cell proliferation, apoptosis, metabolism and protein synthesis, which are closely associated with the activation of PI3K/AKT signaling, which subsequently promotes the transcription of downstream pro-oncogenic target genes such as c-Myc and HIF-1 (77)