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Abstract Severe cutaneous adverse reactions (SCARs), which include StevensJohnson syndrome and toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (also known as drug-induced hypersensitivity syndrome), acute generalized exanthematous pustulosis, and generalized bullous fixed drug eruption, are life-threatening conditions

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g , The indicated siRNAs were introduced into H1299 cells