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Figure S3, C)

Unlike many cofactors that directly participate in redox reactions, zinc's biological role largely involves structural stabilization and catalytic activity, making it indispensable in processes such as transcription, signal transduction, immune function, and apoptosis [5] (Tables 1 and 2)

CHRIS MASTERJOHN: Well, wherever its been measured in heart, its there

A high amount of GSSG indicates a cell has suffered oxidative stress, a process believed to contribute to cell aging, breakdown, malfunction (such as cancer) and eventual death