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Blocking GLN metabolism with the GLS inhibitor CB-839 results in GSH depletion [56, 57]

In the presence of NADPH, GSH reductase converts GSSG to GSH which is utilized in the previous reaction and produces even more TNB

Iodoacetic acid, mustard gas (a poisonous gas), lead, mercury, arsenic and other heavy metal salts are complexed to have an integrated detoxification effect