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Later on Kisspeptin-based studies have identified a role in idiopathic hypogonadotropic hypogonadism, hypothalamic amenorrhoea, hyperprolactinaemia, in vitro fertilization, polycystic ovarian syndrome and psychosexual disorders

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The figure shows the precursors of L-methylmalonyl-CoA: Fatty acids and amino acids can be metabolized to propionyl-CoA, which is converted to D-methylmalonyl-CoA and then to L-methylmalonyl-CoA

This type of anemia is caused by a lack of the intrinsic factor needed to support red blood cell production