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For DDCs regulated primarily as medicinal products, the Common Technical Document (CTD) format, established by the International Council for Harmonization (ICH), is required for marketing authorisation applications in various regions

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HCQ and CQ exert their immunomodulatory effects by inhibiting TLR7 and TLR9 signaling, which plays a crucial role in the pathogenesis of autoimmune diseases such as SLE (101103)

Conclusions This study demonstrates the effectiveness of various ML models in predicting fragrance categories, with particular emphasis on the superior performance of the structural (ST) model that utilizes 2D Morgan fingerprints derived from 3D MolBlock geometries