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Accessed 16 May 202 Daniel L, Karam A, Franco CH, Conde C, de Morais AS, Mosnier J, Fonta I, Villareal WJ, Pradines B, Moreira DRM, Navarro M (2023) Metal(triphenylphosphine)-Atovaquone complexes: synthesis, antimalarial activity, and suppression of heme detoxification

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Deficient glutamate clearance drives neuronal damage in neurotoxic disorders such as WernickeKorsakoff encephalopathy or hepatic encephalopathy 137,138,139 , whereas diminished K + buffering together with insufficient glutamate clearance leads to spreading depression, migraine and epilepsy 140,141,142

We observed that the GSSG-mediated learning defect in the nmr-1(ak4) mutant was rescued by the expression of nmr-1 driven by the glr-1 promoter but not the tdc-1 promoter (Fig