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however, because information on aspartame exposure was collected before the occurrence of disease in the prospective cohort studies, the resulting non-differential (with respect to cancer outcome) misclassification would tend to bias results towards the null

By the time chyme passes from the ileum into the large intestine, it is essentially indigestible food residue (mainly plant fibers like cellulose), some water, and millions of bacteria

The decrease in absorbance reflects the scavenging activity of the antioxidant on the DPPH radical (Glin et al

Notably, although gcs-1 induction is impaired in CSN-deficient animals (Figures 3A,B, 2B upper panel), the high basal gcs-1 expression and increased expression of other phase 2 detoxification genes, e.g., gst-7 (Figure 2B lower panel, see Additional file 2: Figure S5), is sufficient to confer increased oxidative stress resistance (Figures 2C and 3C) [17]