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The spectra demonstrated here were performed at short echo times to capture a wide range of metabolites, with the presence of 2HG also suggested, but not reliably measured, due to high CRLB values

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The immobility time was defined as the amount of time that rats were suspended passively and remained completely motionless ( Sample Collection and Preparation After the final TST, the rats were decapitated under anesthesia (10 mg/kg of 20% urethane)

Mice with knockout of the IGF-1 receptor ( Igf1r ) in their pre-osteoblastic cells showed lower bone mass and mineral deposition rates than wild-type mice