Figure 2 Besides to reduced free zinc levels, zinc binding to MTs directly protects the sulfhydryl groups of MTs from oxidation
ORCID: Affiliation: 2 Cell Biology and Physiology, Translational Research Unit of Excellence CSIR, Indian Institute of Chemical Biology, Kolkata 700091, West Bengal, India ORCID: Affiliation: 1 Centre for Excellence in Molecular Biology and Regenerative Medicine, Department of Biochemistry, JSS Medical College, JSS Academy of Higher Education & Research, Mysore 570015, Karnataka, India ORCID: Affiliation: 1 Centre for Excellence in Molecular Biology and Regenerative Medicine, Department of Biochemistry, JSS Medical College, JSS Academy of Higher Education & Research, Mysore 570015, Karnataka, India ORCID: Affiliation: 3 Department of Respiratory Medicine, JSS Medical College, JSS Academy of Higher Education & Research, Mysore 570015, Karnataka, India Email: [email protected]
Furthermore, a study has demonstrated neuron-selective delivery of microRNA using a D3-peptide-conjugated nanopolymer injected into the tail vein in an AD mouse model [63]
In 1020% of patients, hepatic steatosis progresses to a more advanced state called MASH, which is characterized by the presence of hepatic steatosis ( 5% hepatocytes), inflammation, and hepatocyte injury (ballooning) with or without fibrosis
