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[0235] Embodiment 228: A method for treatment of cancer comprising the steps of contacting a genetically engineered T cell (CAR-Jcell) according to embodiment according to any one of embodiments 201-205, wherein with a cancer cell of a mammal, and inducing apoptosis of the cancer cell

The 177191 fragment was identified as the lipolytic active site, and a tyrosine residue was added at the N-terminus to enhance stability

Br J Cancer 90 : 22562260 Jatoi A, Murphy BR, Foster NR, Nikcevich DA, Alberts SR, Knost JA, Fitch TR, Rowland KM (2006) Oxaliplatin and capecitabine in patients with metastatic adenocarcinoma of the esophagus, gastroesophageal junction and gastric cardia: a phase II study from the North Central Cancer Treatment Group

We have previously reported that GCLM KO mice have lower GSH/GSSG and Cys/CySS redox ratios in plasma, resulting in positive thiol reduction potentials, i.e., more oxidized thiol redox states