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Enhanced endothelial cell proliferation, migration, and tube formation were observed in laboratory studies accompanying the animal experiments

We are finalizing the added paragraph (c)(5) with a modification to replace the term plan of care with plan of treatment. We recognize that we have used the term plan of care and POC in our preamble discussion in the CY 2025 PFS proposed rule and in this final rule, and consider plan of care and plan of treatment to have the same meaning

ARA 290 also benefited the lipid profile, with an improvement in the cholesterol-HDL ratio, in part, as a result of an increase in HDL levels

An IV infusion is delivered in clinic and allows a higher dose to enter the bloodstream directly, which is why it is often chosen when a fuller, faster onset is the goal