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Industrial application of Kefiran products Kefiran is an exopolysaccharide bound to the milk kefir grains and has receiving a great interest among various industries due to its versatility and generally recognised as safe.Thoreux and Schmucker (2001) have found that kefiran could serve as a binding agent, fat replacer, emulsifier, thickening agent, stabilizer, gelling agent, and water binding in the food industry

314, 315 On the other hand, it has recently been shown that CDDP resistance is significantly influenced by non-transformed mesenchymal stem cells and other components of the tumor stroma, including proteins of the extracellular matrix and immunosuppressive cell populations

Small 15(46):e1903153

Consequently, ACSL4 is considered a critical 'gatekeeper' enzyme for ferroptosis, as its expression level and activity cellular sensitivity to ferroptosis