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In patients with chronic kidney disease, reduced reabsorption of carnitine can affect the availability of carnitine in muscles, leading to skeletal muscle atrophy and decreased exercise endurance [262]

However, it is the fate of the newly freed acetyl group that makes ALCAR so therapeutically valuable for neurological health

Finally, one trial in 239 participants already suffering from chemotherapy-induced peripheral neuropathy reported a reduction in the severity of neuropathic symptoms with ALCAR (3 g/day for eight weeks) compared to placebo (93)

Amino acids can be further used by the body to create hormones, enzymes, neurotransmitters, antibodies and nutrient carriers