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PMID: 29338567

Recent research has underscored the need to comprehend the molecular mechanisms of disulfidptosis, particularly regarding cancer treatment, as targeting disulfide metabolism could open up new therapeutic strategies ( FIGURE 1 3.2 Specific mechanism of SLC7A11 in disulfidptosis The abnormal accumulation of intracellular disulfides in SLC7A11 high cells during glucose deprivation triggers a novel form of cell death, which is distinct from both the apoptosis and ferroptosis