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Jan 8 2020;21(2)doi:10.3390/ijms21020382

While tesamorelin is not on the FDA 503A Bulk Drug Substances List, it remains eligible for compounding under Section 503A because it is an active component of an FDA-approved drug (Egrifta) [5]

Limited experimental evidence from animal and tissue cultures suggest that IGF-I complexed with IGFBP-1 and -2 may leave the circulation, although the extent and importance is unclear (Bar 1990)