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In addition to persulfides (RSS ), polysulfides (RS(S) n S ) have also been reported to occur in biological systems and could arise from the reaction of H 2 S with derivatives of existing persulfides 19,20

The reaction mixture was incubated in the dark at room temperature for 20 min, and the concentration of released inorganic phosphate (Pi) was measured by absorbance at 850 nm with a microplate absorbance reader (FlexStation 3, Molecular Devices)

38 In melanoma, XBP1 facilitates the ubiquitination and degradation of Mfn2, which attributes to mitochondrial fission and mitophagy under ER stress

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