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It has been demonstrated that in animals with ALDH4A1 mutation, vitamin E and vitamin C supplementation can reverse the inhibition of ATPase activity by hyperprolinemia, and appropriate use of antioxidants can also be helpful to reduce neurotoxicity [19]

PMID: 31850132

Phase 3 clinical trials are under way (see ClinicalTrials.gov for current registered studies), and whilst early Phase 2 results are encouraging, retatrutide is not legally available as a prescribed medicine in the UK outside of approved clinical trial settings