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Treatment for B12 deficiency without neurological involvement: For patients with haematological manifestations only (macrocytic anaemia) or asymptomatic deficiency, the regimen is hydroxocobalamin 1mg intramuscularly three times weekly for two weeks (total of six injections), followed by maintenance of 1mg every three months for life

If patients continue to have seizures despite folic acid supplementation, additional antiseizure medicatoins should be considered

A 1mL (100 unit) insulin syringe works for most tirzepatide dosing ranges

The Precision Peptide Genetic Test ($99 add-on after first month) identifies genetic variants in 14 pathways affecting nutrient metabolism and absorption, including variants like GIPR rs1800437 and GLP1R rs6923761