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Tissue oxygenation measured with near-infrared spectroscopy during normobaric and hyperbaric oxygen breathing in healthy subjects

Administration of Sativex an approved oromucosal spray (Health Canada and various European health agencies) containing THC (5 mg/kg) and CBD (5 mg/kg) for the treatment of symptoms associated with MSreduced astrocyte reactivity and decreased the expression of pro-inflammatory cytokines released by microglia in a mouse model of MS (Feli et al., 2015)

Prados-Torres A Article: BRAIN RESEARCH

This is associated with small reductions in muscular glucose uptake and oxidation, which could reflect substrate competition between glucose and fatty acids (i.e., the glucose/fatty acid cycle) (Figure 7)