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The eyes are continually exposed to light in order to gather information from the outside environment

Clinical translation requires addressing challenges including cell-type specificity, development of disease-specific ferroptosis biomarkers, optimization of combination regimens, and careful safety assessment to avoid unintended effects such as myelosuppression or hepatorenal toxicity

Protection of midbrain dopaminergic neurons by the end-product of purine metabolism uric acid: potentiation by low-level depolarization