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Tinospora cordifolia , another medicinal plant, has been used to relieve the urotoxic effect of cyclophosphamide through the alteration of Glutathione (GSH) and cytokine levels ( Uncaria tomentosa Uncaria tomentosa belongs to the Rubiaceae family, commonly known as ua de gato or cats claw due to its curved hooks (Naseer et al., 2014)

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1 The incidence of melasma is increasing among adult women all around the world, said principal investigator Helio Miot, MD, PhD, a Professor of Dermatology at Unesp Botucatu, Sao Paulo state, Brazil, who noted that researchers have hypothesized that contraceptive pills, air pollution, and visible light exposure may be causing this increase