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doi: 10.3389/fmed.2022.760852 Received 18 August 2021 Accepted 05 January 2022 Published 08 February 2022 Volume 9 - 2022 Edited by Anupam Mitra, University of California, Davis, United States Reviewed by Irina Khamaganova, Pirogov Russian National Research Medical University, Russia

Yes, it is FDA approved

Capsaicin attenuates SREBP-1 signaling, thereby repressing downstream adipogenic pathways and reinforcing inhibition of fatty acid synthesis (11, 117, 118)

Using proton nuclear magnetic resonance metabolomics, our research team observed that the liver concentrations of glycogen, glucose and lactate in TX mice were notably elevated compared to those in the control group (131)