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PLMT may have unilateral or bilateral leg involvement, and the onset of pain almost invariably precedes the onset of involuntary movements

It is the purer, biologically-preferred version of vitamin B12 that is naturally found in food and can be absorbed and used by the body immediately

Nevertheless, supplementation should ideally be guided by clinical assessment and, where appropriate, blood testing to confirm deficiency before commencing long-term high-dose therapy

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