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however, many people still don't fully understand precisely why inflammation lies at the root of most health concerns plaguing Americans today

Proceedings of the National Academy of Sciences

In another study of schizophrenic patients (N=84), Berk et al 16 undertook a randomized, double-blind, placebo-controlled trial and found that NAC, administered at 1g twice daily for 24 weeks, was a moderately effective augmentation strategy and resulted in improvement in the study scales assessing positive and negative symptoms as well as overall functioning

translation to oral dietary-supplement design requires caution due to route-dependent bioavailability and brain exposure differences