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Targeted therapies, including TNF- inhibitors and IL-6 receptor antagonists, effectively reduce inflammation and improve outcomes through cytokine blockade (Smolen, 2020)

Hum Exp Toxicol 42:9603271231171642

The progression makes the disease even more deadly

(57) found that mustard gas exposure triggered ROS overproduction, upregulation of the ferroptosis gene ACSL4 promoted lipid peroxidation, and downregulation of SLC7A11 and GPX4 weakened cellular defense