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Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles

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Residual-Solvent Testing Appropriate gas-chromatography or other validated methods should assess solvents used during synthesis and purification

In contrast to the rapid onset of remissions observed after diabetes induction with alloxan, 64 onset of remissions with diazoxide was delayed and began about 2 weeks after the start of treatment