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J Headache Pain 22(1):55 Zielman R, Wijnen JP, Webb A et al (2017) Cortical glutamate in migraine

Core-shell nanoparticle based poly (lactate-glycolic) acid (PLGA) was prepared by encasing water-soluble catalase (Cat) to decompose H2O2 into O2, and imiquimote (R837), a toll-like receptor-7 agonist, was loaded into the shell