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Recent findings suggest that this macrophage transition is, at least partially, mediated through lactylation, a post-translational modification where lactate groups are added to lysine residues of proteins [134]

Angiotensin-converting enzyme 2 (ACE2) expression increases with age in patients requiring mechanical ventilation

(II) Despite the intracellular GSH being significantly consumed in the cases stated in this review, it is difficult to completely deplete GSH via these strategies