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(iii) Motor neuron disease: o Data from a patient with MND, primary lateral sclerosis (PLS) variant

All participants gave full informed written consent and underwent an MRS scan and a computerised cognitive assessment

Tumor necrosis factor (TNF) receptor-associated factor (TRAF) When TLRs trigger TRIF activation, the tumor necrosis factor (TNF) receptor-associated factor (TRAF) reacts by escalating the NF-B pathway and the release of inflammatory cytokines